phenobarbital boosts toxicity of ifosfamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. CYP3A4 inducers may possibly enhance the metabolism of ifosfamide to its Energetic alkylating metabolites.Hypnotic doses of barbiturates do not look to impair uterine exercise appreciably through labor. Complete anesthetic doses … Read More